Publications
- Qiao Jin, Nicholas Wan, Robert Leaman, Shubo Tian, Zhizheng Wang, Yifan Yang, Zifeng Wang, Guangzhi Xiong, Po-Ting Lai, Qingqing Zhu, Benjamin Hou, Maame Sarfo-Gyamfi, Gongbo Zhang, Aidan Gilson, Balu Bhasuran, Zhe He, Aidong Zhang, Jimeng Sun, Chunhua Weng, Ronald Summers, Qingyu Chen, Yifan Peng, Zhiyong Lu. Entry-level guide to the use of large language models for medical research. Nature Protocols 2026: 1-12.
- Balu Bhasuran, Prosperi M, Hanna K, Petrilli J, Washington CJ, He Z. Evaluation of causal reasoning for large language models in contextualized clinical scenarios of laboratory test interpretation. NPJ Digit Med. 2026 Apr 23. doi: 10.1038/s41746-026-02632-3. Epub ahead of print. PMID: 42020503.Full text available at npj Digital Medicine
- Zhe He, Balu Bhasuran, Mia Liza A. Lustria, Karim Hanna, Michael Killian, Cindy Shavor, Mandy Dailey, Sai Sidharth Manikandan, Xiao Luo. Generating Question Prompt Lists From Electronic Health Record Data Using Large Language Models: Iterative Evaluation Study. Journal of Medical Internet Research 2026;28:e87280.
- Qiao Jin, Balu Bhasuran, Angelique Deville, Yonghui Wu, Karim Hanna, Zhiyong Lu, Zhe He. A Curated Dataset for Question Answering on Laboratory Test Reference Ranges and Interpretation. Scientific Data 2026.
- M. Prosperi, S. Rancati, Y. Guo, J. Guo, R.M. Radwan, M. Salemi, J. Bian, B. Bhasuran, E.F. Egelund, J. Janelle, P. Manavalan. Consistency in causal reasoning for large language models in scenarios of HIV antiretroviral treatment, drug interactions, and side effects. npj Digital Medicine 2026.
- Aejin Lee, Rajesh Das, Ashlee Huang, Balu Bhasuran, Zhe He. A Comparative Study of Machine Learning and Language Model Approaches for Classifying Mental Health Disorders. In 2026 IEEE 14th International Conference on Healthcare Informatics (ICHI), pp. 631-640. IEEE 2026.
- Balu Bhasuran, Forhan Bin Emdad, Mohammad Ishtiaque Rahman. Evaluating Large Language Models for RNA Interaction Extraction: A Comparative Study on Biomedical Research. Natural Language Processing in Healthcare Informatics: Challenges and Future Directions. Bentham Science Publishers, 2026: 80-94.
- Iyappan Ramalakshmi Oviya, Guruprasath Manika Rameshbabu, Shree Prasad Muthukrishnan, Balu Bhasuran, Tharun Kaarthik Gunasekaran Kumutha, Sudeesh Kumar Venkatesh, Shalini Deena Dhayalan. Identifying lncRNA–Disease Association Based on Dormant Factor Model. Medinformatics 2025.
- I. R. Oviya, B. Bhasuran, D. Soni, R. Mohanty, J. C. Harshini, K. Gurnani, S. M. Varrshini. GRU-CNN Hybrid Model Approach to Classify Human Brain Emotion using EEG Dataset. In 2025 Third International Conference on Networks, Multimedia and Information Technology (NMITCON), pp. 1-5. IEEE 2025.
- S. Manoharan, O. Ramalakshmi Iyappan, A. Prabahar, B. Bhasuran, K. Raja. Gut-lung axis microbiome: Towards precision medicine in respiratory disorders. World Academy of Sciences Journal 2025;7(5):88.
- B. Bhasuran, G. Murugesan, J. Natarajan. Literature-Based Discovery (LBD): Towards Hypothesis Generation and Knowledge Discovery in Biomedical Text Mining. Medinformatics 2025;2(4):241-255.
- X. Wang, H. Ouyang, B. Bhasuran, X. Luo, K. Hanna, M. L. A. Lustria, Z. He. Lab-AI: using retrieval augmentation to enhance language models for personalized lab test interpretation in clinical medicine. In 2025 IEEE 13th International Conference on Healthcare Informatics (ICHI), pp. 359-368. IEEE 2025.
- I. R. Oviya, S. A. Rasool, B. Bhasuran. Enhanced Underwater Object Detection Using Deep Neural networks. In 2024 15th International Conference on Computing Communication and Networking Technologies (ICCCNT), pp. 1-9. IEEE 2024.
- Balu Bhasuran, Abdulkadhar, S., & Natarajan, J. (2026). Unraveling the Biomarker Prospects of High-Altitude Diseases: Insights from Biomolecular Event Network Constructed Using Text Mining. Medinformatics. Full text available atMedinformatics
- Balu Bhasuran, Jin, Q., Xie, Y., Yang, C., Hanna, K., Costa, J., Shavor, C., Han, W., Lu, Z. and He, Z., 2025. Preliminary analysis of the impact of lab results on large language model generated differential diagnoses. npj Digital Medicine, 8(1), p.166. npj Digital Medicine Full text available at npj Digital Medicine
- Balu Bhasuran, Katharina Schmolly, Yuvraaj Kapoor, Nanditha Lakshmi Jayakumar, Raymond Doan, Jigar Amin, Stephen Meninger, Nathan Cheng, Robert Deering, Karl Anderson, Simon W Beaven, Bruce Wang, Vivek A Rudrapatna. Reducing diagnostic delays in acute hepatic porphyria using health records data and machine learning Journal of the American Medical Informatics Association.Full text available at JAMIA
- Vivek A Rudrapatna and Balu Bhasuran. Methods for improving the diagnosis of rare diseases using electronic health records data and systems for same World Intellectual Property Organization Full text available at WIPO
- Balu Bhasuran, Sharanya Manoharan, Oviya Ramalakshmi Iyyappan, Gurusamy Murugesan, Archana Prabahar, Kalpana Raja. Large Language Models and Genomics for Summarizing the Role of microRNA in Regulating mRNA Expression Biomedicines.Full text available at Biomedicines
- Zhe He, Balu Bhasuran, Qiao Jin, Shubo Tian, Karim Hanna, Cindy Shavor, Lisbeth Garcia Arguello, Patrick Murray, Zhiyong Lu. Quality of Answers of Generative Large Language Models Versus Peer Users for Interpreting Laboratory Test Results for Lay Patients: Evaluation Study Journal of Medical Internet Research26 (2024): e56655.Full text available at JMIR
- Anna L Silverman, Balu Bhasuran, Arman Mosenia, Fatema Yasini, Gokul Ramasamy, Imon Banerjee, Saransh Gupta, Taline Mardirossian, Rohan Narain, Justin Sewell, Atul J Butte, Vivek A Rudrapatna. Accurate, Robust, and Scalable Machine Abstraction of Mayo Endoscopic Subscores from Colonoscopy Reports Inflammatory Bowel Diseases, izae068.Full text available at IBD
- Perseus V Patel, Amy Zhang, Balu Bhasuran, Vignesh G Ravindranath, Melvin B Heyman, Sofia G Verstraete, Atul J Butte, Michael J Rosen, Vivek A Rudrapatna, ImproveCareNow Pediatric IBD Learning Health System. Real-world effectiveness of ustekinumab and vedolizumab in TNF-exposed pediatric patients with ulcerative colitis Journal of Pediatric Gastroenterology and Nutrition, Full text available at JPGN
- Anna L Silverman, Madhumita Sushil, Balu Bhasuran, Dana Ludwig, James Buchanan, Rebecca Racz, Mahalakshmi Parakala, Samer El‐Kamary, Ohenewaa Ahima, Artur Belov, Lauren Choi, Monisha Billings, Yan Li, Nadia Habal, Qi Liu, Jawahar Tiwari, Atul J Butte, Vivek A Rudrapatna, Algorithmic Identification of Treatment-Emergent Adverse Events From Clinical Notes Using Large Language Models: A Pilot Study in Inflammatory Bowel Disease Clinical Pharmacology & Therapeutics, Full text available at CPT
- Balu Bhasuran, Shadera Slatter, Gail Fernandes, Boshu Ru, Joe Yang, Xiao Zhang, Ravi Shankar, Jin Ge, Vivek Rudrapatna, S1394 NASHDetection: A Natural Language Processing Method for Identifying Patients With Non-alcoholic Steatohepatitis Using Clinical Notes The American Journal of Gastroenterology, Full text available at ACG
- Balu Bhasuran, Shadera Slatter, Gail Fernandes, Boshu Ru, Joe Yang, Xiao Zhang, Ravi Shankar, Vivek Rudrapatna,Jin Ge. S1395 Uncontrolled Diabetes and Hypertension Are Associated With the Risk of New-Onset Cirrhosis in Patients With Nonalcoholic Steatohepatitis The American Journal of Gastroenterology, Full text available at ACG
- Abhivyakti Yadav, Balu Bhasuran, IR Oviya. A Novel Approach for Classifying DNA Barcodes Using Ensemble NLP Models 2023 International Conference on Research Methodologies in Knowledge Management, Artificial Intelligence and Telecommunication EngineeringFull text available at IEEE
- Abhiram Kunchapu, IR Oviya, Balu Bhasuran. Precision Enhanced Breast Cancer Prediction Using Deep Learning Models 2023 International Conference on Artificial Intelligence for Innovations in Healthcare Industries (ICAIIHI)Full text available at IEEE
- Balu Bhasuran, and Jeyakumar Natarajan. Automatic extraction of gene-disease associations from literature using joint ensemble learning. PloS one. 2018 Jul 26;13(7):e0200699.Full text available at Plos One
- Balu Bhasuran, Gurusamy Murugesan, Sabenabanu Abdulkadhar, and Jeyakumar Natarajan. "Stacked ensemble combined with fuzzy matching for biomedical named entity recognition of diseases." Journal of biomedical informatics 64 (2016): 1-9.Full text available at JBI
- Balu Bhasuran, and Jeyakumar Natarajan. "DisGeReExT: a knowledge discovery system for exploration of disease–gene associations through large-scale literature-wide analysis study." Knowledge and Information Systems (2023): 1-25.Full text available at KAIS
- Balu Bhasuran, Devika Subramanian, and Jeyakumar Natarajan. "Text Mining and Network Analysis to Find Functional Associations of Genes in High Altitude Diseases." Computational Biology and Chemistry (2018).Full text available at CBAC
- Balu Bhasuran "BioBERT and Similar Approaches for Relation Extraction." Biomedical Text Mining. New York, NY: Springer US, 2022. 221-235.Full text available at Biomedical Text Mining
- Balu Bhasuran "Combining Literature Mining and Machine Learning for Predicting Biomedical Discoveries." Biomedical Text Mining. New York, NY: Springer US, 2022. 123-140.Full text available at Biomedical Text Mining
- Silverman, Anna L., Balu Bhasuran, Arman Mosenia, Fatema Yasini, Saransh Gupta, Narbe Mardirossian, Rohan Narain, Justin L. Sewell, Atul Butte, and Vivek A. Rudrapatna. "ACCURATE, ROBUST, AND SCALABLE ABSTRACTION OF MAYO ENDOSCOPIC SUBSCORES FROM COLONOSCOPY REPORTS." In GASTROENTEROLOGY, vol. 162, no. 7, pp. S618-S619. 1600 JOHN F KENNEDY BOULEVARD, STE 1800, PHILADELPHIA, PA 19103-2899 USA: WB SAUNDERS CO-ELSEVIER INC, 2022. Full text available at GASTROENTEROLOGY
- Balu Bhasuran, and Jeyakumar Natarajan.(2019) Distant Supervision for Large-Scale Extraction of Gene–Disease Associations from Literature Using DeepDive. In: Bhattacharyya S., Hassanien A., Gupta D., Khanna A., Pan I. (eds) International Conference on Innovative Computing and Communications. Lecture Notes in Networks and Systems, vol 56. Springer, Singapore. Full text available at ICICC
- Subramanian, Devika, Balu Bhasuran, and Jeyakumar Natarajan. "Genomic analysis of RNA-Seq and sRNA-Seq data identifies potential regulatory sRNAs and their functional roles in Staphylococcus aureus." Genomics (2018).Full text available at Genomics
- Maroli, Nikhil,Balu Bhasuran, Jeyakumar Natarajan, and Ponmalai Kolandaivel. "The potential role of procyanidin as a therapeutic agent against SARS-CoV-2: a text mining, molecular docking and molecular dynamics simulation approach." Journal of Biomolecular Structure and Dynamics (2020): 1-16. Full text available at JBSD
- Abdulkadhar, Sabenabanu, Balu Bhasuran, and Jeyakumar Natarajan. "Multiscale Laplacian graph kernel combined with lexico-syntactic patterns for biomedical event extraction from literature." Knowledge and Information Systems (2020): 1-31.Full text available at KAIS
- Natarajan, Jeyakumar, Balu Bhasuran, and Gurusamy Murugesan. "Big Data Analytics: A Text Mining Perspective and Applications in Biomedicine and Healthcare." Big Data Applications in Industry 4.0. Auerbach Publications 367-408. Full text available at Big Data Analytics
- Gnanasegar, S. M.,Balu Bhasuran, and J. Natarajan. "A long short-term memory deep learning network for MRI based Alzheimer’s disease dementia classification." J Appl Bioinforma Comput Biol 9: 6. doi: 10.37532/jabcb. 2020.9 (6) 187 (2020): 2. Full text available at JABCB
- Maroli, Nikhil, Naveen Kumar Kalagatur, Balu Bhasuran, Achuth Jayakrishnan, Renuka Ramalingam Manoharan, Ponmalai Kolandaivel, Jeyakumar Natarajan, and Krishna Kadirvelu. "Molecular Mechanism of T-2 Toxin-Induced Cerebral Edema by Aquaporin-4 Blocking and Permeation." Journal of chemical information and modeling 59, no. 11 (2019): 4942-4958. Full text available at JCIM
- Gurusamy Murugesan, Sabenabanu Abdulkadhar, Balu Bhasuran, and Jeyakumar Natarajan. "BCC-NER: bidirectional, contextual clues named entity tagger for gene/protein mention recognition." EURASIP Journal on Bioinformatics and Systems Biology 2017, no. 1 (2017): 7. Full text available at JBSB